Chromatid macrocoiling and chromosome compaction
نویسندگان
چکیده
منابع مشابه
Chromosome Condensation: DNA Compaction in Real Time
Mitotic chromosomes must be organised into a highly ordered and compacted form to allow proper segregation of DNA during each round of cell division. Two new studies report observations of DNA compaction by eukaryotic and bacterial condensin molecules in real time using magnetic and optical trapping micromanipulation techniques.
متن کاملDynamics of chromosome compaction during mitosis.
We have quantitatively studied the space-time dynamics of mitotic chromosome compaction in cultured amphibian cells. After collecting digital phase-contrast images we have done digital image analysis to study spatial correlations in density. We find a characteristic distance at which the strongest correlations occur, which provides a quantitative measure of the size of patches of dense chromati...
متن کاملBIOLOGICAL SCIENCES: Biophysics and Computational Biology Mitotic chromosome compaction via active loop extrusion Short title: Chromosome compaction via loop extrusion
During cell division chromosomes are compacted in length by more than a hundred-fold. A wide range of experiments demonstrated that in their compacted state, mammalian chromosomes form arrays of closely stacked consecutive ~100Kb loops. The mechanism underlying the active process of chromosome compaction into a stack of loops is unknown. Here we test the hypothesis that chromosomes are compacte...
متن کاملChromatid and Chromosome Type Breakage-Fusion-Bridge Cycles
During the development of disomic additions of rye (Secale cereak L.) chromosomes to wheat (Triticum aestivum L.), two reverse tandem duplications on wheat chromosomes 3D and 4A were isolated. By virtue of their meiotic pairing, the reverse tandem duplications initiated the chromatid type of the breakagefusion-bridge (BFB) cycle. This BFB cycle continued through pollen mitoses and in the early ...
متن کاملChromosome condensation and sister chromatid pairing in budding yeast
We have developed a fluorescent in situ hybridization (FISH) method to examine the structure of both natural chromosomes and small artificial chromosomes during the mitotic cycle of budding yeast. Our results suggest that the pairing of sister chromatids: (a) occurs near the centromere and at multiple places along the chromosome arm as has been observed in other eukaryotic cells; (b) is maintai...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Hereditas
سال: 2008
ISSN: 0018-0661
DOI: 10.1111/j.1601-5223.1984.tb00099.x